Exendin-4 A Potential Therapeutic Strategy For Alzheimer'S Disease And

Dec 15, 2023 ·Given the substantial body of evidence supporting the neuroprotectivepotentialof exendin-4in various research models, this article is dedicated to exploring the promising role of exendin-4as atherapeuticagent for the treatment and management ofAlzheimer'sdiseaseand Parkinson'sdisease.

Apr 15, 2026 ·Thetherapeuticapplication of Ex-4inAlzheimer'sdisorders will need the successful completion of meticulously designed, adequately powered, longer-duration trials that focus on appropriate patient populations and incorporate sensitive,disease-modifying endpoints.

Download Citation |Exendin‐4: A potential therapeutic strategy for Alzheimer's disease andParkinson'sdisease| Neurodegenerative disorders, which affect millions worldwide, are marked by a ...

Aug 5, 2022 ·Taken together, Exendin-4attenuated Aβ (1-42) toxicity in the C. elegans model of AD via decreasing the expression and the accumulation of Aβ (1-42). Exendin-4exhibited the ability of antioxidant stress through DAF-16. With continuous research, Exendin-4would becomea potentialtherapeuticstrategyfor treating AD.

Moreover,exendin‐4's neuroprotective effects have been reported in several preclinical studies.Exendin‐4's diversetherapeutictargets suggest itspotentialtherapeuticuses in neurodegenerative ailments likeAlzheimer'sdiseaseand Parkinson'sdiseaseand have garnered an increasing amount of attention.

Thus, based solely on the present study, we cannot solidly establish thepotentialof nose-to-brain delivery of exendin-4as atherapeuticstrategyfor AD, because the characteristics of SAMP8 are different from the pathology of AD patients.

Exendin-4's diversetherapeutictargets suggest itspotentialtherapeuticuses in neurodegenerative ailments likeAlzheimer'sdiseaseandParkinson'sdiseaseandhave garnered an increasing amount of attention.

Exendin-4isapotentialtherapeuticagent for wound healing, especially in diabetic patients, since it enhances angiogenesis, collagen production, and cellular proliferation.